NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: T-901
Compound Name: (±)-Tetrabenazine
Alternative Name: (±)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinoline
Abbreviation: 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
PubChemID: 6018
CAS: 58-46-8
Molecular Formula: C19H27NO3
Biological Activity: Reversible monoamine depleting agent, used to treat chorea associated with Huntington's disease and hyperkinetic movement disorders.
References: Jankovic, J.; Beach, J., Neurology, 1997, 48, 358-362. Ondo, W.G.; Hanna, P.A.; Jankovic, J., Amer. J. Psych., 1999, 156, 1279-1281.
Last Updated 2021-04-12 11:17 AM
Structure of T-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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