NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: SR 142948
NIMH Code: S-902
Alternative Name: 2-[[5-(2,6-Dimethoxyphenyl)-1-(4-(3-N’,N’-dimethylaminopropyl)-N-methylcarbamoyl)-2-isopropylphenyl)-1H-pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid hydrochloride
Abbreviation: 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid hydrochloride
Indications: Neurotensin receptor antagonist
Package Sizes:
References: Gully, D.; Labeeuw, B.; Boigegrain, R.; Oury-Donat, F.; Bachy, A.; Poncelet, M.; Steinberg, R.; Suaud-Chagny, M. F.; Santucci, V.; Vita, N.; Pecceu, F.; Labbe-Jullie, C.; Kitabgi, P.; Soubrie, P.; Le Fur, G.; Maffraud, J. P., J. Pharmacol. Exp. Ther., 1997, 280, 802-812. Boigegrain, R.; Molimard, J. C.; Gully, D.; Labeeuw, B.; Jeanjean, F.; Sanofi, S. A., 1996, Patent WO 9632382.
CAS: 184162-64-9
Molecular Formula: C39H52ClN5O6
HBA: 8
HBD: 2
RotB: 13
PubChemID: 5311451
AlogP: -2.3102815
TPSA: 126.23
Activity: Neurotensin receptor antagonist
Comments: CAS Number and PubChem ID are for the base.
Last Updated 2021-04-12 09:24 AM
Structure of S-902
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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