NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: R-901
Compound Name: Risperidone
Alternative Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Abbreviation: 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
PubChemID: 5073
CAS: 106266-06-2
Molecular Formula: C23H27FN4O2
Biological Activity: Serotonin 5HT2 and dopamine D2 antagonist, an atypical antipscyhotic used to treat schizophrenia, bipolar disorder, and irritability associated with autism
References: Leucht, S.; Cipriani, A.; Spineli, L.; Mavridis, D.; Orey, D.; Richter, F.; Samara, M.; Barbui, C.; Engel, R.R.; Geddes, J.R.; Kissling, W.; Stapf, M.P.; Lässig, B.; Salanti, G.; Davis, J.M., Lancet, 2013, 382, 951-962. Rattehalli, R.D.; Zhao, S.; Li, B.G.; Jayaram, M.B.; Xia, J.; Sampson, S., Cochrane Database Syst. Rev., 2016, 12, CD006918.
Last Updated 2021-04-09 02:05 PM
Structure of R-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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