NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: L-901
Compound Name: beta-Lactotensin
Alternative Name: L-histidyl-L-isoleucyl-L-arginyl-L-leucine
Abbreviation: 3 TFA • H-His-Ile-Arg-Leu-OH
PubChemID: 11570130
CAS: 138828-79-2
Molecular Formula: C30H46F9N9O11
Biological Activity: Neurotensin receptor subtype 2 agonist.
References: Yamauchi, R.; Usui, H.; Yunden, J.; Takenaka, Y.; Tani, F.; Yoshikawa, M., Biosci. Biotechnol. Biochem., 2003, 67, 940-943. Yamauchi, R.; Sonoda, S.; Jinsmaa, Y.; Yoshikawa, M., Life Sci., 2003, 73, 1917-1923.
Comments: CAS Number and PubChem ID are for the base. The sample molecular weight (879.73) is for the tris(trifluoroacetate). The molecular weight (anhydrous) of the peptide itself is 537.67. Peptide content (by weight): 54.8%. The degree of solvation (excess trifluoroacetic acid and water) may vary from lot to lot, and over time.
Last Updated 2021-03-01 08:49 AM
Structure of L-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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