NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: beta-Lactotensin
NIMH Code: L-901
Alternative Name:
Abbreviation: 3 TFA • H-His-Ile-Arg-Leu-OH
Indications: neurotensin agonist active at the NT2 receptor
Package Sizes:
References: R. Yamauchi, H. Usui, J. Yunden, Y. Takenaka, F. Tani and M. Yoshikawa, Characterization of beta-lactotensin, a bioactive peptide derived from bovine beta-lactoglobulin, as a neurotensin agonist, Biosci. Biotechnol. Biochem., 67(4), 940-943 (2003); R. Yamauchi, S. Sonoda, Y. Jinsmaa and M. Yoshikawa, Antinociception induced by beta-lactotensin, a neurotensin agonist peptide derived from beta-lactoglobulin, is mediated by NT2 and D1 receptors, Life Sci. 73(15), 1917-1923 (2003).
Molecular Formula: C30H46F9N9O11
HBA: 10
HBD: 9
RotB: 17
AlogP: -5.0599303
TPSA: 241.2
Comments: The sample molecular weight (879.73) is for the tris(trifluoroacetate). The molecular weight (anhydrous) of the peptide itself is 537.67. Peptide content (by weight): 54.8%. The degree of solvation (excess trifluoroacetic acid and water) may vary from lot to lot, and over time.
Last Updated 2008-11-11 02:50 PM
Structure of L-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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