NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: FK866
NIMH Code: F-901
Alternative Name: (E)-N-[4-(1-benzoylpiperidine-4-yl)butyl]-3-(pyridin-3-yl)acrylamide
Indications: nicotinamide phosphoribosyltransferase inhibitor
Package Sizes:
References: E. Biedermann, M. Hasmann, R. Loser, B. Rattel, F. Reiter, B. Schein, K. Seibel and K. Vogt, International Patent WO 97/48397 (June 20, 1997); M. Hasmann and I. Schemainda, FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis, Cancer Res., 63, 7436-7442 (2003).
CAS: 201034-75-5
Molecular Formula: C24H29N3O2
HBA: 3
HBD: 1
RotB: 8
PubChemID: 6914657
AlogP: 3.0211
TPSA: 62.3
Last Updated 2008-11-11 02:43 PM
Structure of F-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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