NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-903
Compound Name: SIB-1553A
Alternative Name: 4-[2-(1-Methylpyrrolidin-2-yl)ethylsulfanyl]phenol hydrochloride
PubChemID: 9881989
CAS: 191611-89-9
Molecular Formula: C13H20ClNOS
Biological Activity: Nicotinic acetylcholine receptor agonist with selectivity for beta-4 subunit-containing receptors; possible cognitive enhancer
References: Vernier, J. M.; El-Abdellaoui, H.; Holsenback, H.; Cosford, N. D. P.; Bleicher, L.; Barker, G.; Bontempi, B.; Chavez-Noriega, L.; Menzaghi, F.; Rao, T. S.; Reid, R.; Sacaan, A. I.; Suto, C.; Washburn, M.; Lloyd, G. K.; McDonald, I. A., J. Med. Chem., 1999, 42, 1684-1686. Vernier, J.M.; Mcdonald, I.A., 1997, Patent WO 9719059.
Last Updated 2021-04-12 09:31 AM
Structure of S-903
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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