NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-McN-5652 S-Desmethyl-S-butyryl Ester D-Tartrate
NIMH Code: M-901
Alternative Name: (6S,10bR)-(+)-cis-1,2,3,5,6,10b-Hexahydro-6-[(4-butyrylthio)phenyl]pyrrolo[2,1-a]isoquinoline D-Tartrate
Indications: Precursor to [11C]-(+)-McN-5652
Package Sizes:
References: J. Zessin, P. Gucker, S. M. Ametamey, J. Steinbach, P. Brust, F. X. Vollenweider, B. Johannsen and P. A. Schubiger, Efficient synthesis of enantiomerically pure thioester precursors of [11C]McN-5652 from racemic McN-5652, J. Labelled Cmpd. Radiopharm., 42, 1301-1312 (1999).
CAS: 167548-65-4
Molecular Formula: C26H31NO7S
HBA: 3
HBD: 0
RotB: 5
AlogP: 5.0403
TPSA: 45.61
Comments: The D-tartrate salt is said to have a longer shelf life than the free base (M-706). This salt is also easier to handle.
Last Updated 2008-11-11 11:29 AM
Structure of M-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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