NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-(2R,3R,11bR)-9-O-Desmethyl-alpha-dihydrotetrabenazine
NIMH Code: T-902
Alternative Name:
Abbreviation: (+)-(2R,3R,11bR)-9-O-Desmethyl-alpha-DTBZ
Indications: Starting material for synthesis of carbon-11 labeled (+)-alpha-dihydrotetrabenazine ([11C]DTBZ)
Package Sizes:
References: M. R. Kilbourn, PET Radioligands for vesicular neurotransmitter transporters, Med. Chem. Res., 5, 113-126 (1994); M. R. Kilbourn, L. C. Lee, M. J. Heeg and D. M. Jewett, Absolute configuration of (+)-alpha-dihydrotetrabenazine, an active metabolite of tetrabenazine, Chirality, 9, 59-62 (1997).
CAS: 5220-98-4
Molecular Formula: C18H27NO3
HBA: 4
HBD: 2
RotB: 3
AlogP: 2.3283
TPSA: 52.93
Last Updated 2015-02-11 09:39 AM
Structure of T-902
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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