NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: T-904
Compound Name: (-)-Tetrabenazine
Alternative Name: (-)-(3S,11bS)-9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
Abbreviation: (3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
PubChemID: 11634155
CAS: 1026016-84-1
Molecular Formula: C19H27NO3
Biological Activity: Dopamine depleting agent; optical isomer of tetrabenazine
References: Yao, Z.; Wei, X.; Wu, X.; Katz, J.L.; Kopajtic, T.; Greig, N.H.; Sun, H., Eur. J. Med. Chem., 2011, 46, 1841-1848. Yu, Q.; Luo, W.; Deschamps, J.; Holloway, H.W.; Kopajtic, T.; Katz, J.L.; Brossi, A.; Greig, N.H., ACS Med. Chem. Lett., 2010, 1, 105-109.
Last Updated 2021-04-12 11:24 AM
Structure of T-904
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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