NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: SIB-1508Y
NIMH Code: S-905
Alternative Name: (S)-5-Ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine Maleate
Indications: Agonist for neuronal nicotinic acetylcholine-gated ion channels
Package Sizes:
References: L. S. Bleicher, N. D. P. Cosford, A. Herbaut, J. S. McCallum and I. A. McDonald, A practical and efficient synthesis of the selective neuronal acetylcholine-gated ion channel agonist (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y), J. Org. Chem., 63, 1109-1118 (1998).
CAS: 192231-16-6
Molecular Formula: C16H18N2O4
HBA: 2
HBD: 0
RotB: 2
PubChemID: 10968648
AlogP: 1.3193
TPSA: 16.13
Last Updated 2008-11-11 11:17 AM
Structure of S-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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