NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-905
Compound Name: SIB-1508Y
Alternative Name: (S)-5-Ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate, (Z)-but-2-enedioic acid;3-ethynyl-5-[(2S)-1-methylpyrrolidin-2-yl]pyridine maleate
Abbreviation: Altinicline maleate
PubChemID: 11954277
CAS: 192231-16-6
Molecular Formula: C16H18N2O4
Biological Activity: alpha-4-beta-2 subtype selective neural nicotinic acetylcholine receptor agonist
References: Bleicher, L. S.; Cosford, N. D. P.; Herbaut, A.; McCallum, J. S.; McDonald, I. A., J. Org. Chem., 1998, 63, 1109-1118. Comins, D.L.; Smith, E.D., Tetrahedron Lett., 2006, 47, 1449-1451.
Last Updated 2021-04-12 09:40 AM
Structure of S-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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