NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: SKF-81297 Hydrobromide
NIMH Code: S-906
Alternative Name: (±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine Hydrobromide, (±)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol Hydrobromide
Abbreviation:
Indications: dopamine agonist
Package Sizes:
References: F. R. Pfeiffer, J. W. Wilson, J. Weinstock, G. Y. Kuo, P. A. Chambers, K. G. Holden, R. A. Hahn, J. R. Wardell, Jr., A. J. Tobia, P. E. Setler and H. M. Sarau, Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, J. Med. Chem., 25, 352-358 (1982); J. L. Neumeyer, N. Baindur, H. B. Niznik, H. C. Guan and P. Seeman, (±)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahudro-1H-3-benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship, J. Med. Chem., 34, 3366-3371 (1991).
CAS: 71636-61-8
Molecular Formula: C16H17BrClNO2
HBA: 4
HBD: 3
RotB: 1
PubChemID: 11957706
AlogP: 1.5352654
TPSA: 52.49
Activity: Dopamine Agonist
Comments:
Last Updated 2008-11-11 03:02 PM
Structure of S-906
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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