NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: SKF-82958 Hydrobromide
NIMH Code: S-907
Alternative Name: (±)-3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine Hydrobromide, (±)-3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol Hydrobromide
Abbreviation: (±)-Chloro-APB Hydrobromide, (±)-6-Chloro-APB Hydrobromide
Indications: dopamine agonist
Package Sizes:
References: F. R. Pfeiffer, J. W. Wilson, J. Weinstock, G. Y. Kuo, P. A. Chambers, K. G. Holden, R. A. Hahn, J. R. Wardell, Jr., A. J. Tobia, P. E. Setler and H. M. Sarau, Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, J. Med. Chem., 25, 352-358 (1982); J. L. Neumeyer, N. Baindur, H. B. Niznik, H. C. Guan and P. Seeman, (±)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahudro-1H-3-benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship, J. Med. Chem., 34, 3366-3371 (1991).
CAS: 80751-65-1
Molecular Formula: C19H21BrClNO2
HBA: 4
HBD: 2
RotB: 3
PubChemID: 9909521
AlogP: 3.973002
TPSA: 43.7
Activity: Dopamine Agonist
Comments:
Last Updated 2008-11-11 03:02 PM
Structure of S-907
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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