NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (-)-alpha-Dihydrotetrabenazine
NIMH Code: D-905
Alternative Name:
Indications: Optical isomer of putative tetrabenazine metabolite alpha-dihydrotetrabenazine
Package Sizes:
References: M. R. Kilbourne, L. C. Lee, M. J. Heeg and D. M. Jewett, Absolute configuration of (+)-alpha-dihydrotetrabenazine, an active metabolite of tetrabenazine, Chirality, 9, 59-62 (1997); M. Kilbourne, L. Lee, T. Vander Borght, D. Jewett and K. Frey, Binding of alpha-dihydrotetrabenazine to the vasicular monoamine transporter is stereospecific, Eur. J. Pharmacol., 278, 249-252 (1995).
CAS: 3466-75-9
Molecular Formula: C19H29NO3
HBA: 4
HBD: 1
RotB: 4
PubChemID: 123836
AlogP: 2.36
TPSA: 41.93
Last Updated 2008-11-11 11:03 AM
Structure of D-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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