NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: M-903
Compound Name: [(-)-(R)-Methyl 4-[(3,4-dichlorophenyl)acetyl]-3-[(1-pyrrolidinyl)methyl]-1-piperazinecarboxylate fumarate
Alternative Name: Methyl (3R)-4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate
Abbreviation: GR103545 fumarate
PubChemID: 6603856
CAS: 126766-42-5
Molecular Formula: C19H25Cl2N3O3
Biological Activity: Kappa-opioid receptor agonist
References: Soukara, S.; Maier, C.A.; Predoiu, U.; Ehret, A.; Jackisch, R.; Wuensch, B., J. Med. Chem., 2001, 44, 2814-2826. Shannon, H.E.; Eberle, E.L.; Mitch, C.H.; McKinzie, D.L.; Statnick, M.A., Neuropharmacology, 2007, 53, 930-941.
Last Updated 2021-03-01 03:55 PM
Structure of M-903
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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