NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: O-901
Compound Name: Olanzapine
Alternative Name: 2-Methyl-4-(4-methyl-1-piperainyl)-10H-thieno[2,3-b][1,5]benzodiazepine
PubChemID: 135398745
CAS: 132539-06-1
Molecular Formula: C17H20N4S
Biological Activity: Dopamine and serotonin receptor inhibitor, an atypical antipsychotic used to treat schizophrenia and bipolar disorder
References: Harvey, R.C.; James, A.C.; Shields, G.E., CNS Drugs, 2016, 30, 27-39. Duggan, L.; Fenton, M.; Rathbone, J.; Dardennes, R.; El-Dosoky, A.; Indran, S., Cochrane Database Syst. Rev.
Last Updated 2021-03-17 08:17 AM
Structure of O-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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