NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: L-902
Compound Name: Lamotrigine
Alternative Name: 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
PubChemID: 3878
CAS: 84057-84-1
Molecular Formula: C9H7Cl2N5
Biological Activity: Voltage-sensitive sodium channel inhibitor, an anticonvulsant used to treat seizures and bipolar disorder.
References: French, J.A.; Kanner, A.M.; Bautista, J.; Abou-Khalil, B.; Browne, T.; Harden, C.L.; Theodore, W.H.; Bazil, C.; Stern, J.; Schachter, S.C.; Bergen, D.; Hirtz, D.; Montouris, G.D.; Nespeca, M.; Gidal, B.; Marks, W.J.; Turk, W.R.; Fischer, J.H.; Bourgeois, B.; Wilner, A.; Faught, R.E.; Sachdeo, R.C.; Beydoun, A.; Glauser, T.A., Neurology, 2004, 62, 1261-1273. Goldberg, J.F.; Calabrese, J.R.; Saville, B.R.; Frye, M.A.; Ketter, T.A.; Suppes, T.; Post, R.M.; Goodwin, F.K., J. Clin. Psych., 2009, 70, 1273-1280.
Last Updated 2021-03-01 08:52 AM
Structure of L-902
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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