NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-908
Compound Name: Duloxetine hydrochloride
Alternative Name: (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine hydrochloride
PubChemID: 60834
CAS: 136434-34-9
Molecular Formula: C18H19NOS
Biological Activity: Serotonin & norepinephrine reuptake inhibitor, used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain
References: Geddes, J.R.; Ioannidis, J.P.A.; Tajika, A.; Shinohara, K.; Imai, H.; Hayasaka, Y.; Takeshima, N.; Egger, M.; Higgins, J.P.T., Lancet, 2018, 391, 1357-1366. Wong, D.T.; Robertson, D.W.; Bymaster, F.P.; Krushinski, J.H.; Reid, L.R. Life Sci., 1988, 43, 2049–2057.
Last Updated 2021-02-19 10:18 AM
Structure of D-908
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

Content © 2014. «RTI International».