NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-909
Compound Name: Sertraline hydrochloride
Alternative Name: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride
PubChemID: 63009
CAS: 79559-97-0
Molecular Formula: C17H18Cl3N
Biological Activity: Serotonin reuptake inhibitor; used to treat used to treat major depressive disorder, obsessive–compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder
References: LĂ©pine, J.P.; Goger, J.; Blashko, C.; Probst, C.; Moles, M.F.; Kosolowski, J.; Scharfetter, B.; Lane, R.M., Int. Clin. Psychopharmacol., 2000, 15, 263-271. Sarges, R.; Tretter, J.R.; Tenen, S.S.; Weissman, A., J. Med. Chem., 1973, 16, 1003-1011.
Last Updated 2021-04-12 09:54 AM
Structure of S-909
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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