NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: Z-903
Compound Name: Ziprasidone hydrochloride
Alternative Name: 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one hydrochloride
PubChemID: 219099
CAS: 122883-93-6
Molecular Formula: C21H22Cl2N4OS
Biological Activity: Dopamine D2 , Serotonin 5-HT2A, 5HT1D receptor antagonist, 5-HT1 receptor agonist; an atypical antipsychotic used to treat schizophrenia and bipolar disorder.
References: Nicolson, S.E.; Nemeroff, C.B., Neuropsychiatr. Dis. Treat., 2007, 3, 823-834. Schmidt, A.W.; Lebel, L.A.; Howard, H.R.; Zorn, S.H., Eur. J. Pharmacol., 2001, 425, 197-201.
Last Updated 2021-04-14 08:34 AM
Structure of Z-903
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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