NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-909
Compound Name: Donepezil
Alternative Name: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
PubChemID: 3152
CAS: 120014-06-4
Molecular Formula: C24H29NO3
Biological Activity: Reversible acetylcholinesterase inhibitor, used to treat Alzheimer's disease
References: Birks, J.S.; Harvey, R.J., Cochrane Database Syst. Rev., 2018, 6, CD001190. Davies, P.; Maloney, A.J., Lancet, 1976, 2, 1403.
Last Updated 2021-02-19 10:20 AM
Structure of D-909
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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