NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: Donepezil
NIMH Code: D-909
Alternative Name: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Abbreviation:
Indications: Reversible acetylcholinesterase inhibitor, used to treat Alzheimer's disease
Package Sizes:
References: Birks, J.S.; Harvey, R.J., Cochrane Database Syst. Rev., 2018, 6, CD001190. Davies, P.; Maloney, A.J., Lancet, 1976, 2, 1403.
CAS: 120014-06-4
Molecular Formula: C24H29NO3
HBA: 4
HBD: 0
RotB: 6
PubChemID: 3152
AlogP: 3.6928
TPSA: 38.77
Activity: Reversible acetylcholinesterase inhibitor, used to treat Alzheimer's disease
Comments:
Last Updated 2021-02-19 10:20 AM
Structure of D-909
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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