NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 2-Methyl-4-(1-piperazinyl)-10H-thieno-[2,3-b][1,5]benzodiazepine (N-Desmethylolanzapine)
NIMH Code: D-910
Alternative Name: N-Desmethylolanzapine
Indications: Metabolite of Olanzapine
Package Sizes:
References: Chakrabarti, J.; Hotten, T. M.; Tupper, D. E. U.S. Patent 5 627 178, 1997; Calligaro, D. O.; Fairhurst, J.; Hotten, T. M. Bioorg. Med. Chem. Lett. 1997, 7, 25-30.
Molecular Formula: C16H18N4S
HBA: 5
HBD: 2
RotB: 0
AlogP: 2.7238
TPSA: 67.9
Last Updated 2008-11-11 12:29 PM
Structure of D-910
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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