NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: M-909
Compound Name: R-(–)-[2-(Diphenyl)methanesulfinyl]acetamide
Alternative Name: 2-[(R)-benzhydrylsulfinyl]acetamide
Abbreviation: R-(–)-Modafinil; Armodafinil
PubChemID: 9690109
CAS: 112111-43-0
Molecular Formula: C15H15NO2S
Biological Activity: Dopamine reuptake inhibitor; (R)-(-) enantiomer of Modafinil with a longer duration of action and increased wakefulness promoting activity
References: Pristinzano, T.; Podobinski, J.; Tidgewell, K.; Luo, M.; Swenson, D. Tetrahedron: Asymmetry 2004, 15, 1053-1058. Darwish, M.; Kirby, M.; Hellriegel, E. T.; Robertson Jr, P. Clin. Drug. Investig., 2009, 29, 613-623.
Comments: DEA Schedule IV controlled substance.
Last Updated 2021-03-03 08:44 AM
Structure of M-909
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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