NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: M-913
Compound Name: 2-[4’-(Methylamino)phenyl]-6-hydroxybenzothiazole
Alternative Name: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
Abbreviation: 6-OH-BTA-1
PubChemID: 10171487
CAS: 566169-93-5
Molecular Formula: C14H12N2OS
Biological Activity: Aggregated amyloid protein ligand; thioflavin-T analog; PET imaging agent Pittsburgh Compound-B (PIB) reference standard.
References: Mathis, C. A.; Wang, Y.; Holt, D. P.; Huang, G. F.; Debnath, M. L.; Klunk, W. E. J. Med. Chem. 2003, 46, 2740-2754. Cai, L.; Qu, B.; Hurtle, B.T.; Dadiboyena, S.; Diaz-Arrastia, R.; Pike, V.W, ACS Chem. Neurosci., 2016, 7, 897-911.
Last Updated 2021-03-03 08:53 AM
Structure of M-913
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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