NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 2-{4-[4-(2-Hydroxyphenyl)piperazin-1-yl]butyl}-4-methyl-1,2,4-triazine-3,5-(2H,4H)-dione (Desmethyl CUMI-101)
NIMH Code: D-912
Alternative Name: Desmethyl CUMI-101
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Indications: 5-HT1A receptor PET imaging ligand precursor
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References: 1) Kumar, J. S.; Prabhakaran, J.; Majo, V. J.; Milak, M. S.; Hsiung, S. C.; Tamir, H.; Simpson, N. R.; Van Heertum, R. L.; Mann, J. J.; Parsey, R. V. Eur. J. Nucl. Med. Mol. Imaging 2007, 34, 1050-1060. 2) Kumar, J. S.; Majo, V. J.; Hsiung, S. C.; Milak, M. S.; Liu, K. P.; Tamir, H.; Prabhakaran, J.; Simpson, N. R.; Van Heertum, R. L.; Mann, J. J.; Parsey, R. V. J. Med. Chem. 2006, 49, 125-134.
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Last Updated 2010-04-21 11:16 AM
Structure of D-912
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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