NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-912
Compound Name: 2-{4-[4-(2-Hydroxyphenyl)piperazin-1-yl]butyl}-4-methyl-1,2,4-triazine-3,5-(2H,4H)-dione
Alternative Name: 2-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione
Abbreviation: Desmethyl CUMI-101
PubChemID: 59738835
CAS: 903528-73-4
Molecular Formula: C18H25N5O3
Biological Activity: 5-HT1A receptor PET imaging ligand precursor
References: Kumar, J. S.; Prabhakaran, J.; Majo, V. J.; Milak, M. S.; Hsiung, S. C.; Tamir, H.; Simpson, N. R.; Van Heertum, R. L.; Mann, J. J.; Parsey, R. V. Eur. J. Nucl. Med. Mol. Imaging 2007, 34, 1050-1060. Kumar, J. S.; Majo, V. J.; Hsiung, S. C.; Milak, M. S.; Liu, K. P.; Tamir, H.; Prabhakaran, J.; Simpson, N. R.; Van Heertum, R. L.; Mann, J. J.; Parsey, R. V. J. Med. Chem. 2006, 49, 125-134.
Comments:
Last Updated 2021-02-19 10:25 AM
Structure of D-912
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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