NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: C-918
Compound Name: 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
Alternative Name: 3-cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide
Abbreviation: CDPPB
PubChemID: 11245456
CAS: 781652-57-1
Molecular Formula: C23H16N4O
Biological Activity: Metabotropic glutamate mGluR5 positive allosteric modulator
References: Lindsley, C. W.; Wisnoski, D. D.; Leister, W. H.; O'Brien, J. A.; Lemaire, W.; Williams Jr., D. L.; Burno, M.; Sur, C.; Kinney, G. G.; Pettibone, D. J.; Tiller, P. R.; Smith, S.; Duggan, M. E.; Hartman, G. D.; Conn, P. J.; Huff, J. R. J. Med. Chem. 2004, 47, 5825-5828. Kinney, G. G.; O'Brien, J. A.; Lemaire, W.; Burno, M.; Bickel, D. J.; Clements, M. K.; Chen, T. B.; Wisnoski, D. D.; Lindsley, C. W.; Tiller, P. R.; Smith, S.; Jacobson, M. A.; Sur, C.; Duggan, M. E.; Pettibone, D. J.; Conn, P. J.; Williams Jr., D. L. J. Pharmacol. Exp. Ther. 2005, 313, 199-206.
Last Updated 2021-02-17 03:36 PM
Structure of C-918
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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