NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-917
Compound Name: (R)-(+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
Alternative Name: (R)-(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
Abbreviation: Volinanserin
PubChemID: 5311271
CAS: 139290-65-6
Molecular Formula: C22H28NFO3
Biological Activity: Serotonin 5-HT2A receptor antagonist
References: Kehne, J. H.; Baron, B. M.; Carr, A. A.; Chaney, S. F.; Elands, J.; Feldman, D. J.; Frank, R. A.; van Giersbergen, P. L.; McCloskey, T. C.; Johnson, M. P.; McCarty, D. R.; Poirot, M.; Senyah, Y.; Siegel, B. W.; Widmaier, C. J. Pharmacol. Exp. Ther. 1996, 277, 968-981. Ullrich, T.; Rice, K. C. Bioorg. Med. Chem. 2000, 8, 2427-2432.
Last Updated 2021-02-19 10:45 AM
Structure of D-917
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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