NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-912
Compound Name: N-(1-Methyl-1H-indol-5-yl)-N'-(3-methylisothiazol-5-yl)urea
Alternative Name: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
Abbreviation: SB 204741
PubChemID: 3277600
CAS: 152239-46-8
Molecular Formula: C14H14N4OS
Biological Activity: 5-HT2B receptor antagonist
References: Forbes, I. T.; Jones, G. E.; Murphy, O. E.; Holland, V.; Baxter, G. S. J. Med. Chem. 1995, 38, 855-857. West, J.D.; Carrier, E.J.; Bloodworth, N.C.; Schroer, A.K.; Chen, P.; Ryzhova, L.M.; Gladson, S.; Shay, S.; Hutcheson, J.D.; Merryman, D.W., PLoS One, 2016, 11, e0148657/1-e0148657/18.
Last Updated 2021-04-12 10:04 AM
Structure of S-912
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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