NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: P-905
Compound Name: Methyl (8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol[1,5-a][1,4]benzodiazepin-3-yl)methyl ether
Alternative Name: 8-chloro-3-(methoxymethyl)-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Abbreviation: PWZ-029
PubChemID: 9971547
CAS: 164025-33-6
Molecular Formula: C14H14ClN3O2
Biological Activity: a5 GABAA receptor inverse agonist
References: Savic, M. M.; Clayton, T.; Furtmüller, R.; Gavrilovic, I.; Samardzic, J.; Savic, S.; Huck, S.; Sieghart, W.; Cook, J. M. Brain Res. 2008, 1208, 150-159. Xu, N.Z.; Ernst, M.; Treven, M.; Cerne, R.; Wakulchik, M.; Li, X.; Jones, T.M.; Gleason, S.D.; Morrow, D.; Schkeryantz, J.M.; Rahman, M.T.; Li, G.; Poe, M.M.; Cook, J.M.; Witkin, J.M., Psychopharmacology, 2018, 235, 1151-1161.
Last Updated 2021-04-09 01:22 PM
Structure of P-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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