NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-920
Compound Name: Delorazepam
Alternative Name: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Abbreviation: Chlordesmethyldiazepam
PubChemID: 17925
CAS: 2894-67-9
Molecular Formula: C15H10Cl2N2O
Biological Activity: Active metabolite of the benzodiazepine drugs diclazepam and cloxazolam, GABAA receptor allosteric modulator, anxiolytic, skeletal muscle relaxant, hypnotic and anticonvulsant
References: Zimmermann-Tansella, C.; Tansella, M.; Lader, M. J. Clin. Pharmacol. 1976, 16, 481-488. Govoni, S.F.P.; Spano, P.F.; Trabucchi, M. Psychopharmacology, 1976, 50: 241–244.
Comments: Schedule IV controlled substance
Last Updated 2021-02-23 01:16 PM
Structure of D-920
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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