NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-(4aR,10bR)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b]-1,4-oxazine-9-ol Hydrochloride [(+)-N-Despropyl-PHNO Hydrochloride]
NIMH Code: D-919
Alternative Name: (+)-N-Despropyl-PHNO Hydrochloride
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Indications: Dopamine D2/3 receptors PET ligand labeling precursor.
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References: 1. Wilson, A. A.; McCormick, P.; Kapur, S.; Willeit, M.; Garcia, A.; Hussey, D.; Houle, S.; Seeman, P.; Ginovart, N. J. Med. Chem. 2005, 48, 4153-4160. 2. Willeit, M.; Ginovart, N.; Kapur, S.; Houle, S.; Hussey, D.; Seeman, P.; Wilson, A. A.; Biol. Psychiatry 2006, 59, 389-394. 3. Graff-Guerrero, A.; Willeit, M.; Ginovart, N.; Mamo, D.; Mizrahi, R.; Rusjan, P.; Vitcu, I.; Seeman, P.; Wilson, A. A.; Kapur, S. Hum. Brain Mapp. 2008, 29, 400-410.
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Last Updated 2014-12-23 02:41 PM
Structure of D-919
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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