NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
NIMH Code: D-921
Alternative Name: 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Abbreviation: SA-4503 dihydrochloride; cutamesine dihydrochloride
Indications: Sigma-1 receptor agonist
Package Sizes:
References: Fujimura, K.; Matsumoto, J.; Niwa, M.; Kobayashi, T.; Kawashima, Y.; In, Y.; Ishida, T. Bioorg. Med. Chem. 1997, 5, 1675-1683. 2. Matsuno, K.; Nakazawa, M.; Okamoto, K.; Kawashima, Y.; Mita, S. Eur. J. Pharmacol. 1996, 306, 271-279. Yamaguchi, K.; Shioda, N.; Yabuki, Y.; Zhang, C.; Han, F.; Fukunaga, K., Int. J. Mol. Sci., 2018, 19, 2811/1-2811/15.
CAS: 165377-44-6
Molecular Formula: C23H34Cl2N2O2
HBA: 4
HBD: 2
RotB: 9
PubChemID: 9954941
TPSA: 24.9
Activity: Sigma-1 receptor agonist
Last Updated 2021-02-23 01:20 PM
Structure of D-921
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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