NIMH Code: | D-922 |
Compound Name: | 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N-methyl-2,2-diphenylbutanamide hydrochloride |
Alternative Name: | N-Desmethyl-loperamide hydrochloride |
Abbreviation: | |
PubChemID: | 9805944 |
CAS: | 66164-07-6 |
Molecular Formula: | C28H32Cl2N2O2 |
Biological Activity: | Loperamide metabolite, P-glycoprotein PET reagent reference standard, P-glycoprotein inhibitor |
References: | Lazarova, N.; Zoghbi, S. S.; Hong, J.; Seneca, N.; Tuan, E.; Gladding, R. L.; Liow, J. S.; Taku, A.; Innis, R. B.; Pike, V. W. J. Med. Chem. 2008, 51, 6034-6043. Leopoldo, M.; Nardulli, P.; Contino, M.; Leonetti, F.; Luurtsema, G.; Colabufo, N.A., Expert Opin. Ther. Pat., 2019, 29, 455-461. |
Comments: | CAS Number and PubChem ID are for the base |
Last Updated 2021-02-23 01:24 PM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.