NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-922
Compound Name: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N-methyl-2,2-diphenylbutanamide hydrochloride
Alternative Name: N-Desmethyl-loperamide hydrochloride
PubChemID: 9805944
CAS: 66164-07-6
Molecular Formula: C28H32Cl2N2O2
Biological Activity: Loperamide metabolite, P-glycoprotein PET reagent reference standard, P-glycoprotein inhibitor
References: Lazarova, N.; Zoghbi, S. S.; Hong, J.; Seneca, N.; Tuan, E.; Gladding, R. L.; Liow, J. S.; Taku, A.; Innis, R. B.; Pike, V. W. J. Med. Chem. 2008, 51, 6034-6043. Leopoldo, M.; Nardulli, P.; Contino, M.; Leonetti, F.; Luurtsema, G.; Colabufo, N.A., Expert Opin. Ther. Pat., 2019, 29, 455-461.
Comments: CAS Number and PubChem ID are for the base
Last Updated 2021-02-23 01:24 PM
Structure of D-922
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

Content © 2014. «RTI International».