NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N-methyl-2,2-diphenylbutanamide Hydrochloride (N-Desmethyl-loperamide Hydrochloride)
NIMH Code: D-922
Alternative Name: N-Desmethyl-loperamide Hydrochloride
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Indications: P-glycoprotein PET reagent reference standard.
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References: Lazarova, N.; Zoghbi, S. S.; Hong, J.; Seneca, N.; Tuan, E.; Gladding, R. L.; Liow, J. S.; Taku, A.; Innis, R. B.; Pike, V. W. J. Med. Chem. 2008, 51, 6034-6043.
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Last Updated 2012-02-16 03:11 PM
Structure of D-922
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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