NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: H-910
Compound Name: N-[2-(5-Hydroxy-6-fluoro-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide (6-Fluoro-HIOC)
Alternative Name: 6-Fluoro-HIOC
Abbreviation:
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Biological Activity: Fluorinated HIOC derivative; selective TrkB receptor agonist; neuroprotectant
References: Sompol, P.; Liu, X.; Baba, K.; Paul, K. N.; Tosini, G.; Iuvone, P. M.; Ye, K. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 8844-8849. Shen, J.; Ghai, K.; Sompol, P.; Liu, X.; Iuvone, M.; Ye, K. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 3540-3545.
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Last Updated 2021-02-24 08:30 AM
Structure of H-910
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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