NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: T-911
Compound Name: N-[2-(2-Trifluoromethyl-5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide
Alternative Name: 2-Trifluoromethyl-HIOC
Abbreviation:
PubChemID:
CAS:
Molecular Formula:
Biological Activity: Fluorinated HIOC derivative
References: Sompol, P.; Liu, X.; Baba, K.; Paul, K. N.; Tosini, G.; Iuvone, P. M.; Ye, K. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 8844-8849. Shen, J.; Ghai, K.; Sompol, P.; Liu, X.; Iuvone, M.; Ye, K. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 3540-3545.
Comments: HIOC is a tyrosine receptor kinase B (TrkB) agonist
Last Updated 2021-04-12 12:19 PM
Structure of T-911
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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