NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 5-{4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide Hydrochloride (Vilazodone Dihydrochloride)
NIMH Code: V-904
Alternative Name: Vilazodone Dihydrochloride
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Indications: Antidepressant with a dual mechanism of 5-HT reuptake inhibition and 5-HT1A partial agonism.
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References: 1) Frampton, J. E. CNS Drugs 2011, 25, 615-627. 2) Khan, A. Expert Opin. Investig. Drugs 2009, 18, 1753-1764. 3) Heinrich, T.; Böttcher, H.; Gericke, R.; Bartoszyk, G. D.; Anzali, S.; Seyfried, C. A.; Greiner, H. E.; Van Amsterdam, C. J. Med. Chem. 2004, 47, 4684-4692.
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Last Updated 2013-09-30 10:16 AM
Structure of V-904
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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