NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-6-((R)-2-{2-[4-(4-Chlorophenoxy)piperidin-1-yl]ethyl}pyrrolidine-1-sulphonyl)-1H-indole Hydrochloride (SB-656104-A)
NIMH Code: C-927
Alternative Name: SB-656104-A
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Indications: High-affinity, selective 5-HT7 antagonist.
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References: 1. Forbes, I. T.; Douglas, S.; Gribble, A. D.; Ife, R. J.; Lightfoot, A. P.; Garner, A. E.; Riley, G. J.; Jeffrey, P.; Stevens, A. J.; Stean, T. O.; Thomas, D. R. Bioorg. Med. Chem. Lett. 2002, 12, 3341-3344. 2. Thomas, D. R.; Melotto, S.; Massagrande, M.; Gribble, A. D.; Jeffrey, P.; Stevens, A. J.; Deeks, N. J.; Eddershaw, P. J.; Fenwick, S. H.; Riley, G.; Stean, T.; Scott, C. M.; Hill, M. J.; Middlemiss, D. N.; Hagan, J. J.; Price, G. W.; Forbes, I. T. Br. J. Pharmacol. 2003, 139, 705-714.
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Last Updated 2013-09-30 10:17 AM
Structure of C-927
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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