NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: C-928
Compound Name: (-)-6-((S)-2-{2-[4-(4-Chlorophenoxy)piperidin-1-yl]ethyl}pyrrolidine-1-sulphonyl)-1H-indole Hydrochloride
Alternative Name:
Molecular Formula:
Biological Activity: Isomer of 5-HT7 antagonist SB-656104-A.
References: 1. Forbes, I. T.; Douglas, S.; Gribble, A. D.; Ife, R. J.; Lightfoot, A. P.; Garner, A. E.; Riley, G. J.; Jeffrey, P.; Stevens, A. J.; Stean, T. O.; Thomas, D. R. Bioorg. Med. Chem. Lett. 2002, 12, 3341-3344. 2. Thomas, D. R.; Melotto, S.; Massagrande, M.; Gribble, A. D.; Jeffrey, P.; Stevens, A. J.; Deeks, N. J.; Eddershaw, P. J.; Fenwick, S. H.; Riley, G.; Stean, T.; Scott, C. M.; Hill, M. J.; Middlemiss, D. N.; Hagan, J. J.; Price, G. W.; Forbes, I. T. Br. J. Pharmacol. 2003, 139, 705-714.
Last Updated 2013-09-30 10:18 AM
Structure of C-928
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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