NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: L-905
Compound Name: 9-Isopropyl-N-[3-(trifluoromethyl)benzyl]-9H-purin-6-amine
Alternative Name: 9-propan-2-yl-N-[[3-(trifluoromethyl)phenyl]methyl]purin-6-amine
Abbreviation: Longdaysin
PubChemID: 49830252
CAS: 1353867-91-0
Molecular Formula: C16H16F3N5
Biological Activity: CK1, ERK2 and CDK7 kinases inhibitor that results in a lengthening of circadian periods
References: Kolarski, D.; Sugiyama, A.; Breton, G.; Rakers, C.; Ono, D.; Schulte, A.; Tama, F.; Itami, K.; Szymanski, W.; Hirota, T.; Feringa, B.L., J. Am. Chem. Soc., 2019, 141, 15784-15791. Lee, J.W.; Hirota, T.; Ono, D.; Honma, S.; Honma, K.; Park, K.; Kay, S.A., J. Med. Chem., 2019, 62, 1989-1998.
Last Updated 2021-03-01 08:59 AM
Structure of L-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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