NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-913
Compound Name: 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide
Alternative Name: 2-bromo-N-[4-chloro-3-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]-4,5-dimethoxybenzenesulfonamide
Abbreviation: SB 657510
PubChemID: 11272107
CAS: 474960-44-6
Molecular Formula: C19H22BrClN2O5S
Biological Activity: Selective urotensin-II (UT) receptor antagonist
References: Douglas, S. A.; Behm, D. J.; Aiyar, N. V.; Naselsky, D.; Disa, J.; Brooks, D. P.; Ohlstein, E. H.; Gleason, J. G.; Sarau, H. M.; Foley, J. J.; Buckley, P. T.; Schmidt, D. B.; Wixted, W. E.; Widdowson, K.; Riley, G.; Jin, J.; Gallagher, T. F.; Schmidt, S. J.; Ridgers, L.; Christmann, L. T.; Keenan, R. M.; Knight, S. D.; Dhanak, D. Br. J. Pharmacol. 2005, 145, 620-635. Li, J.; Zhao, P.-P.; Hao, T.; Wang, D.; Wang, Y.; Zhu, Y.-Z.; Wu, Y.-Q.; Zhou, C.-H., J. Endocrinol., 2017, 232, 165-174.
Last Updated 2021-04-12 10:09 AM
Structure of S-913
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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