NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-923
Compound Name: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanamide
Alternative Name: N-Didesmethyl loperamide
PubChemID: 25129795
CAS: 66164-06-5
Molecular Formula: C27H29ClN2O2
Biological Activity: Loperamide metabolite, P-glycoprotein PET ligand labeling precursor
References: Yoshida, K.; Nambu, K.; Arakawa, S.; Miyazaki, H.; Hashimoto, M., Biomed. Mass Spec., 1979, 6, 253-259. Boudhar, A.; Ng, X.W.; Loh, C.Y.; Chia, W.N.; Tan, Z.M.; Nosten, F.; Dymock, B.; Tan, K.S.W., Eur. J. Med. Chem., 2016, 119, 231-249.
Last Updated 2021-02-23 01:27 PM
Structure of D-923
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

Content © 2014. «RTI International».