NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanamide (N-Didesmethyl-loperamide)
NIMH Code: D-923
Alternative Name: N-Didesmethyl-loperamide)
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Indications: P-glycoprotein PET ligand labeling precursor
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References: Lazarova, N.; Zoghbi, S. S.; Hong, J.; Seneca, N.; Tuan, E.; Gladding, R. L.; Liow, J. S.; Taku, A.; Innis, R. B.; Pike, V. W. J. Med. Chem. 2008, 51, 6034-6043.
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Last Updated 2013-09-30 10:19 AM
Structure of D-923
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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