NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: M-920
Compound Name: (+)-4-(2-methoxyphenyl)-3,7,7-trimethyl-2H,4H,5H,6H,7H,8H,9H-pyrazolo[3,4-b]quinolin-5-one
Alternative Name:
Abbreviation: (+)-JB1121
CAS: 1597439-29-6
Molecular Formula: C19H21N3O2
Biological Activity: Serine/threonine kinase glycogen synthase kinase-3 (GSK3) inhibitor
References: Wagner, F.F.; Pan, J.Q.; Dandapani, S.; Germain, A.; Holson, E.; Munoz, B.; Nag, P.P.; Weiwer, M.; Lewis, M.C.; Haggarty, S.J.; Bishop, J.A.; Stegmaier, K.; Banerji, V., 2014, Patent WO 2014059383. Scolnick, E.; Cottrell, J.R.; Wagner, F.F.; Holson, E.; Lewis, M.C.; Bear, M.F.; Stoppel, L.; Heynen, A., 2016, Patent US 20160375006.
Comments: CAS Number is for the racemate
Last Updated 2021-03-03 09:11 AM
Structure of M-920
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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