NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (-)-4-(2-methoxyphenyl)-3,7,7-trimethyl-2H,4H,5H,6H,7H,8H,9H-pyrazolo[3,4-b]quinolin-5-one
NIMH Code: M-921
Alternative Name:
Abbreviation: (-)-JB1121
Indications: Serine/threonine kinase glycogen synthase kinase-3 (GSK3) inhibitor.
Package Sizes:
References: Wagner, F.F.; Pan, J.Q.; Dandapani, S.; Germain, A.; Holson, E.; Munoz, B.; Nag, P.P.; Weiwer, M.; Lewis, M.C.; Haggarty, S.J.; Bishop, J.A.; Stegmaier, K.; Banerji, V., 2014, Patent WO 2014059383. Scolnick, E.; Cottrell, J.R.; Wagner, F.F.; Holson, E.; Lewis, M.C.; Bear, M.F.; Stoppel, L.; Heynen, A., 2016, Patent US 20160375006.
CAS: 1597439-29-6
Molecular Formula: C19H21N3O2
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Activity: Serine/threonine kinase glycogen synthase kinase-3 (GSK3) inhibitor
Comments: CAS Number is for the racemate
Last Updated 2021-03-03 09:13 AM
Structure of M-921
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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