NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 1,3-Bis(8-acetyleno-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine-3-carboxy)propyl diester (XLi-093)
NIMH Code: B-918
Alternative Name: XLi-093
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Indications: Selective alpha5 GABA-A receptor antagonist.
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References: 1. Li, X.; Cao, H.; Zhang, C.; Furtmüeller, R.; Fuchs, K.; Huck, S.; Sieghart, W.; Deschamps, J.; Cook, J. M., J. Med. Chem. 2003, 46, 5567-5570. 2. Savic, M.; Milinkovic, M.; Rallapalli, S.; Clayton, T. Sr.; Joksimovic, S.; Van Linn, M.; Cook, J., Neuropsychopharmacology 2009, 12, 1179-1193.
CAS: 646066-59-3
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Last Updated 2015-01-23 11:28 AM
Structure of B-918
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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