Compound Information Page
| NIMH Code: | B-918 |
| Compound Name: | 1,3-Bis(8-acetyleno-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine-3-carboxy)propyl diester |
| Alternative Name: | XLi-093 |
| Abbreviation: | Bis[8-ethynyl-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid] 1,3-propanediyl ester |
| PubChemID: | 131701296 |
| CAS: | 646066-59-3 |
| Molecular Formula: | C33H26N6O6 |
| Biological Activity: | Selective alpha5 GABA-A receptor antagonist/negative allosteric modulator |
| References: | Li, X.; Cao, H.; Zhang, C.; Furtmüeller, R.; Fuchs, K.; Huck, S.; Sieghart, W.; Deschamps, J.; Cook, J. M., J. Med. Chem. 2003, 46, 5567-5570. Savic, M.; Milinkovic, M.; Rallapalli, S.; Clayton, T. Sr.; Joksimovic, S.; Van Linn, M.; Cook, J., Neuropsychopharmacology 2009, 12, 1179-1193. Xu, N.Z.; Ernst, M.; Treven, M.; Cerne, R.; Wakulchik, M.; Li, X.; Jones, T.M.; Gleason, S.D.; Morrow, D.; Schkeryantz, J.M.; Rahman, M.T.; Li, G.; Poe, M.M.; Cook, J.M.; Witkin, J.M., Psychopharmacology, 2018, 235, 1151-1161. |
| Comments: | Note the structure in PubChem may not be correct |
| Last Updated 2021-02-17 11:37 AM | |
