NIMH Code: | C-930 |
Compound Name: | (2S)-2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid (4-Cl-KYN) trifluoroacetate |
Alternative Name: | L-4-Chlorokynurenine trifluoroacetate; 2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid trifluoroacetate |
Abbreviation: | 4-Cl-KYN TFA |
PubChemID: | 173480 |
CAS: | 75802-84-5 |
Molecular Formula: | C12H12ClF3N2O5 |
Biological Activity: | Prodrug of the glycine binding site NMDA receptor antagonist 7-chlorokynurenine |
References: | Zanos, P.; Piantadosi, S.C.; Wu, H.Q.; Pribut, H.J.; Dell, M.J.; Can, A. Snodgrass, H.R.; Zarate, C.A.; Schwarcz, R.; Gould, T.D., J Pharmacol Exp Ther., 2015, 355, 76-85. Salituro, F. G.; Tomlinson, R. C.; Baron, B. M.; Palfreyman, M. G.; McDonald, I. A.; Schmidt, W.; Wu, H. Q.; Guidetti, P.; Schwarcz, R. J. Med. Chem. 1994, 37, 334-336. |
Comments: | CAS Number and PubChem ID are for the base |
Last Updated 2021-06-02 04:40 PM |
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