NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 8-Chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5H-dibenzo[b,e][1,4]diazepine (JHU37160) Dihydrochloride New!
NIMH Code: J-902
Alternative Name: JHU37160 Dihydrochloride
Abbreviation: J60 2HCl
Indications: DREADD agonist with high affinity and potency for CNS applications.
Package Sizes:
References: 1. DREADD Actuators. PCT application 1,916,892. 2. Bonaventura J, Eldridge MAG, Hu F, et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat Commun. 2019;10(1):4627. 3. Goutaudier R, Coizet V, Carcenac C, Carnicella S. DREADDs: The Power of the Lock, the Weakness of the Key. Favoring the Pursuit of Specific Conditions Rather than Specific Ligands. eNeuro. 2019;6(5):ENEURO.0171-19.2019.
Molecular Formula: C19H22Cl3FN4
Comments: Water soluble
Last Updated 2020-09-10 05:09 PM
Structure of J-902
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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