Compound Information Page
| NIMH Code: | J-902 |
| Compound Name: | 8-Chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5H-dibenzo[b,e][1,4]diazepine (JHU37160) Dihydrochloride New! |
| Alternative Name: | JHU37160 Dihydrochloride |
| Abbreviation: | J60 2HCl |
| PubChemID: | |
| CAS: | |
| Molecular Formula: | C19H22Cl3FN4 |
| Biological Activity: | DREADD agonist with high affinity and potency for CNS applications. |
| References: | 1. DREADD Actuators. PCT application 1,916,892. 2. Bonaventura J, Eldridge MAG, Hu F, et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat Commun. 2019;10(1):4627. 3. Goutaudier R, Coizet V, Carcenac C, Carnicella S. DREADDs: The Power of the Lock, the Weakness of the Key. Favoring the Pursuit of Specific Conditions Rather than Specific Ligands. eNeuro. 2019;6(5):ENEURO.0171-19.2019. |
| Comments: | Water soluble |
| Last Updated 2021-05-28 11:38 AM | |
