NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: T-912
Compound Name: 8-methoxy-3-methyl-1H,2H,3H,4H,5H,6H-azepino[4,5-b]indole (Tabernanthalog) New!
Alternative Name: Tabernanthalog
Abbreviation: TBG
PubChemID: 146026994
Molecular Formula: C14H18N2O
Biological Activity: A non-hallucinogenic agonist of the serotonin 5-HT2A receptor
References: Cameron, L. P.; Tombari, R. J.; Lu, J.; Pell, A. J.; Hurley, Z. Q.; Ehinger, Y.; Vargas, M. V.; McCarroll, M. N.; Taylor, J. C.; Myers-Turnbull, D.; Liu, T.; Yaghoobi, B.; Laskowski, L. J.; Anderson, E. I.; Zhang, G.; Viswanathan, J.; Brown, B. M.; Tjia, M.; Dunlap, L. E.; Rabow, Z. T.; Fiehn, O.; Wulff, H.; McCorvy, J. D.; Lein, P. J.; Kokel, D.; Ron, D.; Peters, J.; Zuo, Y.; Olson, D. E., A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature 2021, 589, 474-479.
Comments: A water-soluble, non-toxic analog of the psychoactive drug ibogaine
Last Updated 2021-06-02 04:36 PM
Structure of T-912
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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