NIMH Code: | J-903 |
Compound Name: | JHU37152 dihydrochloride New! |
Alternative Name: | 8-chloro-11-(4-ethylpiperazin-1-yl)-1-fluoro-5H-dibenzo[b,e][1,4]diazepine |
Abbreviation: | J52 2HCl |
PubChemID: | |
CAS: | 2369979-67-7 (base) |
Molecular Formula: | C19H22Cl3FN4 • 2 H2O |
Biological Activity: | DREADD agonist with high affinity and potency for CNS applications. |
References: | DREADD Actuators. PCT application 1,916,892. Bonaventura, J.; Eldridge, M. A. G.; Hu, F.; et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat. Commun. 2019, 10, 4627. |
Comments: | Water soluble |
Last Updated 2024-05-01 05:02 PM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.