NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: J-904
Compound Name: 8-Chloro-11-(4-ethylpiperazinyl)-5H-dibenzodiazepin-2-ol ([18F]JHU37107 Precursor) New!
Alternative Name: [18F]JHU37107 Precursor
Molecular Formula: C19H21ClN4O
Biological Activity: A precursor to the high potency ligand for DREADD imaging.
References: DREADD Actuators. PCT application 1,916,892. Bonaventura, J.; Eldridge, M. A. G.; Hu, F.; et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat. Commun. 2019, 10, 4627.
Last Updated 2023-11-17 03:32 PM
Structure of J-904
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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